International expansion and buyer-driven commodity chain: the case of TESCO

This paper is prepared within the project ‘The Emerging Industrial Architecture of the Wider Europe; the Co-evolution of Industrial and Political Structures ’ funded by the ESRC programme ‘One Europe or Several?’ * Authors would like to thank Nick von Tunzelmann for his valuable comments in earlier draft versions. Following the collapse of Communism, central European countries have experienced an invasion of foreign investment in many sectors. The sectors that target consumers directly have found an opportunity to gain market share with considerable long-term profit potential. Thus, investments by western retailers are quite large when compared to other industries1. These multinational

The issues of enterprise growth in transition and post-transition period: the case of Polish 'Elektrim'

Case study of Polish company Elektrim illustrates the changing basis of growth of enterprises between the transition and post-transition periods. Elektrim grew primarily through conglomeration in the transition period. After the exhaustion of this mode of growth Elektrim has started to focus on a few core areas (telecoms, cables, energy). The strategic shift to telecommunications has been based on partnerships with foreign firms and it is likely that this will be the pattern in other areas. In this respect, the case of Elektrim shows the importance of internationalisation for the growth of enterprises in CEE. Based on the case study the paper draws several analytical issues: First, Elektrim's shift from conglomeration to focusing suggests that the institutional context, which drives firm strategy in post-socialist economies like Poland, is, perhaps, also changing. Second, in order to grow Elektrim is forced to enter into equity relationships and partnerships like with French Vivendi. This suggests that the possibilities for firm growth in post-socialist economies, like Poland, through generic expansion are still fewer when compared to growth based on mergers & acquisitions or different forms of alliances. Third, Elektrim's relationship with government is complex and refutes the simplified dichotomy of markets vs. governments. This raises the issue of to what extent post-socialist governments operate as a 'compensatory mechanism' on which firms like Elektrim can rely to grow. Fourth, the opening of the CEECs has led to relocations of EU and other MNCs into this region with the result that they are also transferring the oligopolistic competition from EU into new markets. The case of Elektrim shows how CEE companies and goverment regulations become factors in the oligopolistic competition between big EU companies. CEE companies and governments may use this competition to their advantage but also their limited bargaining powers may lead to outcomes unfavourable to them

‘Transformation Triangle’ for SME Productivity and Growth

In the aftermath of the Covid-19 pandemic and Brexit, there is an increased urgency to focus on how we can help SMEs to address the crucial issues of productivity and growth against a growing economic trajectory of soaring energy prices, supply chain problems, labour/skill shortages, and increasing inflation and interest rates. To date, most of the empirical research has focused on factors that enable or hinder SME growth. While there is a robust evidence base, studies do not particularly bridge the gap between this evidence base and its practical use through applied frameworks. This link is important not only to support managerial decision-making but more importantly for policymaking. Based on the findings from our research on SME growth processes, this report generates a framework that addresses possible interventions to overcome the SME drag effect. The framework focuses on the transformational effect of the identified three key areas, namely mindset transformation, strategy transformation and digital transformation. The interdependent but dynamic relationships between these three areas are framed through what we call a ‘Transformation Triangle’ to achieve and sustain SME productivity and growth

Antitumor effect of sFlt-1 gene therapy system mediated by Bifidobacterium Infantis on Lewis lung cancer in mice

Soluble fms-like tyrosine kinase receptor (sFlt-1) is a soluble form of extramembrane part of vascular endothelial growth factor receptor-1 (VEGFR-1) that has antitumor effects. Bifidobacterium Infantis is a kind of non-pathogenic and anaerobic bacteria that may have specific targeting property of hypoxic environment inside of solid tumors. The aim of this study was to construct Bifidobacterium Infantis-mediated sFlt-1 gene transferring system and investigate its antitumor effect on Lewis lung cancer (LLC) in mice. Our results demonstrated that the Bifidobacterium Infantis-mediated sFlt-1 gene transferring system was constructed successfully and the system could express sFlt-1 at the levels of gene and protein. This system could not only significantly inhibit growth of human umbilical vein endothelial cells induced by VEGF in vitro, but also inhibit the tumor growth and prolong survival time of LLC C57BL/6 mice safely. These data suggest that Bifidobacterium Infantis-mediated sFlt-1 gene transferring system presents a promising therapeutic approach for the treatment of cancer